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Video feature: People of the British Isles
What does Britishness mean to a scientist? How does a person from Kent differ from one from the Hebrides? People of the British Isles is a project cataloguing the genetic basis of the entire UK. 08/12/2010
From Human variation > Features
Study confirms gene link to obesity
A new study has provided the first direct evidence that over-activity of a gene called FTO leads to over-eating and obesity in mice. The findings suggest that the gene could be a promising target for developing anti-obesity drugs that decrease the gene's activity. 16/11/2010
From Diagnosing disease > News
Genetic variants linked to increased risk of common gynaecological disease
Research published today identifies two genetic variants that increase the risk of developing endometriosis, a common gynaecological disease. The study provides clues to the origin of this often very painful condition, which has a significant impact on the quality of life of sufferers. 13/11/2010
From Genes and disease > News
Study shows great genetic variation in pancreatic cancer
A new study published recently in 'Nature' reveals in detail the complexity of genetic variation found in pancreatic cancer cells. The ability to identify and understand the early mutations involved with the disease may lead to the discovery of new drug targets. 09/11/2010
From Genes and disease > News
Gene discovery supports link between handedness and language-related disorders
Scientists at the Wellcome Trust Centre for Human Genetics, University of Oxford, have identified a genetic variant which influences whether a person with dyslexia is more skilled with either the left or right hand. The finding identifies a novel gene for handedness and provides the first genetic evidence to support a link between handedness and a language-related disorder. 05/11/2010
From How the body works > News
1000 Genomes Project publishes most comprehensive map to date of human genetic variation
Small genetic differences between individuals help explain why some people are at higher risk than others for developing illnesses such as diabetes or cancer. This week, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic variations, estimated to contain approximately 95 per cent of the genetic variation of any person on Earth. 28/10/2010
From Focus on genes > News
Scientists identify four genetic variants linked to risk of early menopause
Research suggests that four common genetic variants may have a significant impact on the odds of having early menopause. 18/10/2010
From How the body works > News
Is explaining variation in height a tall order?
Hundreds of common genetic variants across the human genome influence adult height, according to a study of over 180 000 individuals published today in the journal 'Nature'. The study itself identifies over a hundred new variants and shows that they are not randomly distributed, but are clustered around genes which have been previously linked to growth. 30/09/2010
From Human variation > News
Taking a genetic view of ADHD
It has recently been discovered that children with ADHD are more likely to have pieces of their DNA duplicated or missing than other children. 30/09/2010
From Diagnosing disease > News
Largest genetic study of asthma points towards better treatments
A large international study has identified several genetic variants that increase susceptibility to asthma in the population. Scientists hope the findings will help to focus efforts for development of better therapies for the illness. 27/09/2010
From Treating disease > News
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Complexity constrains evolution of human brain genes
Despite the explosive growth in size and complexity of the human brain, the pace of evolutionary change among the thousands of genes expressed in brain tissue has actually slowed since the split, millions of years ago, between human and chimpanzee, an international research team reports in the December 26, 2006, issue of the journal, PLOS Biology.
Science Daily
29/12/2007
Commercialization of novel UD gene-repair technology
OrphageniX Inc., a new biotechnology company founded by University of Delaware researchers, has been established in Wilmington to develop and commercialize UD-patented technologies for repairing genes that cause rare, hereditary diseases such as sickle cell anemia and spinal muscular atrophy.
MedicoNews.com
30/04/2007
Researchers help identify new genetic risk factors for Type 2 Diabetes
In the most comprehensive look at genetic risk factors for type 2 diabetes to date, researchers from the University of Michigan, the National Human Genome Research Institute, the University of Southern California, the University of North Carolina, and Finland's National Health Institute, have identified at least four new genetic variants associated with increased risk of diabetes and confirmed existence of another six. The findings are posted in the online edition of the journal Science.
Medical News Today
29/04/2007
Genetic Information Nondiscrimination Act passes house, USA
The House of Representatives passed the Genetic Information Nondiscrimination Act (GINA) of 2007 on Wednesday, April 25. GINA is expected to pass the Senate and be signed into law in the coming months.
Medical News Today
28/04/2007
Patients with rare brain tumor may have genetic predisposition
Genetic susceptibility markedly increases the risk of developing radiation-associated meningioma - a rare brain tumour - according to a study published in the May issue of THE LANCET ONCOLOGY.
rBiotech
28/04/2007
More Type 2 Diabetes genes discovered
Several teams of scientists report discovering more genes linked to Type 2 Diabetes and describe the achievement as bringing science closer to understanding the genetics of the origins and progress of this modern disease. The various papers are published in Science and Nature Genetics this week, 27/04/2007.
Medical News Today
27/04/2007
Obtaining valid consent for doing large genetic studies in developing countries
Genetic studies are providing clues for scientists working on vaccines against HIV, malaria, and TB. But it is crucial, say Dave Chokshi (Wellcome Trust Centre for Human Genetics, University of Oxford) and colleagues in a policy paper in PLoS Medicine, to ensure that those who choose to participate in such research have given their fully informed consent.
Medical News Today
27/04/2007
New understanding of schizophrenia could lead to new treatment approaches
Findings tie together genetic associations, white-matter defects, dopamine abnormalities and disease symptoms. The findings, published online by the Proceedings of the National Academy of Sciences, also demonstrate how two of the dozen or more genes previously linked with schizophrenia may contribute to the disease.
Children’s Hospital Boston
23/04/2007
Scientists identify a candidate gene for osteoporosis - gene may underlie differences between African Americans and Caucasians
Researchers report the identification of a gene that may play a role in susceptibility to osteoporosis-the crippling disease that leads to bone fractures, especially of the hip and spine.
Medical News Today
28/03/2007
Simulated populations used to probe gene mapping for studying complex diseases
More powerful computers are allowing scientists and engineers to conduct simulations that grow more realistic each year. While companies are using these tools to slash the costs of producing everything from airliners to antibiotics, researchers in Houston are using them to refine their search for the genetic causes of disease.
Medical News Today
28/03/2007
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