Explore the technologies that underpin biomedical research.

Sequencing technologies

How have sequencing technologies developed and what does this mean for researchers today? 10/12/09

Animal cloning

The production of genetically-identical animals by nuclear transfer from somatic cells to unfertilised eggs. 08/01/03

Combinatorial library screening

Large collections of chemical compounds that are screened to identify potential new drugs. 08/01/03

DNA sequencing

How to determine the sequence of bases in a DNA molecule. 08/01/03

Genome sequencing

How the full genetic code of an organism is read. 08/01/03

Knockout mice

The inactivation of a specific gene in a mouse. 08/01/03

Mass spectrometry

A high-throughput method for the identification of proteins. 08/01/03

Microarrays and gene expression

Microarrays can be used to analyse the expression of tens of thousands of genes simultaneously. 08/01/03

NMR spectroscopy

Used to determine the structure of molecules including small, soluble proteins. 08/01/03

Polymerase chain reaction

Used to amplifiy a piece of DNA. 08/01/03

SNP typing with DNA chips

Microarrays can be used to determine the particular base present in a single nucleotide polymorphism (SNP). 08/01/03

Transgenic mice

Transgenic mice contain additional foreign DNA in every cell allowing them to be used to study gene function or regulation and to model human diseases. 08/01/03

Two-dimensional polyacrylamide gel electrophoresis

Used to separate complex mixtures of protein, and to characterise differences between related protein samples. 08/01/03