A variable genome
The human genome is remarkably similar between different people, but small differences can have big impacts. What are these variations, and how are they uncovered? |
Haplotype mapping
Haplotypes, groups of closely linked alleles that tend to be inherited together, can be used to map human disease genes very accurately. 20/03/03
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Linkage analysis
Finding the rough position of human disease genes relative to known genetic markers. 20/03/03
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Mutation or polymorphism?
DNA sequence variations are sometimes described as mutations and sometimes as polymorphisms. What is the difference? 20/03/03
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Simple sequence repeats
In some places in the genome, the same sequence is repeated over and over again. 20/03/03
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Single nucleotide polymorphisms (SNPs)
The most common type of variation in the human genome, where a single base differs between individuals. 20/03/03
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