Model organisms

Yeast, fruit flies, nematode worms and mice: just some of the model organisms whose study is bringing insights into the role of genes in the human body.
Features
Image for Why the mouse?
Having ticked off flying, swimming and hopping things, our model organism series turns to Mus musculus: the invaluable mouse. 19/03/04
Features
Image for Why the fly?
Some of the most remarkable discoveries in biology have come from studies of the humble fruit fly. 12/11/02
Features
Exploring the genetics of anxiety. 20/04/07
News
Genome analysis of the red jungle fowl, a wild ancestor of the domestic chicken, is completed by an international consortium. 09/12/04
News
Researchers have deleted 3 per cent of the mouse genome, but the mice show no apparent ill effects. 20/10/04
Features
How do you make a taste bud? Genetics is beginning to reveal the recipe. 08/08/04
News
The draft sequence of the genome of the Brown Norway strain of the laboratory rat (Rattus norvegicus) is completed. 31/03/04
Features
The remarkable contribution of the African clawed frog to our understanding of development. 29/01/04
News
No obesity or diabetes for a mouse engineered to be immune to a high-fat diet. 02/09/03
Features
First the fly, then the worm. This time, our series of articles exploring model organisms turns its attention to the zebrafish. 21/08/03
Features
A postgenomics programme in Oxford and Canberra aims to identify the genes controlling the mouse immune system. 01/07/03
Technology centre
The inactivation of a specific gene in a mouse. 08/01/03
News
An international consortium has published a draft sequence and analysis of the genome of the common mouse, Mus musculus. 05/12/02
Background
Frogs and chickens provide good experimental models of vertebrate development and have therefore been adopted as model organisms even though they are not suitable for genetic analysis. 29/08/02
Background
The nematode Caenorhabditis elegans is a very simple animal that can be handled like a microbe but it shares many genes and molecular pathways with humans. 29/08/02
Background
The mouse is closely related to humans so most human genes have functional mouse counterparts and the genome is organised in a very similar manner. 29/08/02
Background
Baker's yeast is one of the simplest eukaryotic organisms but many essential cellular processes are conserved between yeast and humans. 29/08/02
Background
The fruit fly Drosophila melanogaster has the longest history of any model organism and has been widely used to study genetics and developmental biology. 29/08/02
Background
Model organisms are easy to breed and study in the laboratory, and are used to obtain information about other species that cannot be studied directly. 29/08/02
Background
Two species of fish are widely used as model organisms: the zebrafish primarily because of its experimental and genetic amenability, and the pufferfish because of its extraordinarily compact genome. 29/08/02
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