Treating disease

Genetics-based research is already leading to new therapies and to a greater understanding of how genetic variations influence response to drugs.

news

For the first time, scientists have cleanly corrected a human gene mutation in a patient's stem cells. The result brings the possibility of patient-specific therapies closer tobecoming a reality. 13/10/11

Researchers have discovered a genetic variant that significantly increases the risk of carriers being allergic to a common medication for epilepsy. 24/03/11

features

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We spoke to Professors Andrew Hattersley and Frances Ashcroft about their research into diabetes, and met some people affected by the condition whose lives have been transformed as a result of this research. 27/07/09
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An ACE inhibitor that widens blood vessels and helps to relieve high blood pressure. 22/09/04

background

Image for A brief history of clinical trials
Today's clinical trials evolved from trial-by-error studies of new treatments. 22/09/04
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Establishing the effectiveness and safety of new treatments by testing human volunteers. 30/07/03
"It would surprise me enormously if in 20 years the treatment of cancer had not been transformed." Mike Stratton
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