The Genome Sequence

How DNA sequencing is uncovering the secrets encoded within the 3 billion nucleotides of the human genome.

News

Image for Largest study of genomes and cancer treatments releases first results
The largest study to correlate genetics with response to cancer drugs has released its first results. The UK-US collaboration's work is a step towards more personalised cancer treatment. 19/07/10
Image for Celebrating a 'decade of discovery' since the Human Genome Project
Leading scientists who helped map the human genome celebrate a decade of discovery since the first draft with the launch of the UK 10 000 Genomes Project. 25/06/10
Image for Wellcome Trust launches study of 10 000 human genomes in UK
The Wellcome Trust has launched a project to decode the genomes of 10 000 people over three years - one of the largest genome sequencing programmes ever. 25/06/10
Image for ICGC to sequence 25 000 cancer genomes
The International Cancer Genome Consortium is to decode the genomes from 25 000 cancer samples and create a resource of freely available data. 15/04/10
Image for 1000 Genomes Project
An international research consortium has announced the 1000 Genomes Project, an ambitious effort to sequence the genomes of at least 1000 people to create the most detailed and medically useful catalogue to date of human genetic variation. 23/01/08
Image for Rhesus macaque genome helps illustrate what makes us human
The genome of the rhesus macaque monkey provides insights into how humans are genetically different from our primate relatives. 12/04/07
Image for $10 million prize offered for rapid genome sequencing
The Archon X PRIZE for Genomics has been offered to the first team of scientists to devise a form of rapid genetic sequencing that allows them to decode 100 human genomes in just ten days. 09/10/06
Image for Chromosome 1 sequenced
Researchers at the Wellcome Trust Sanger Institute and colleagues in the UK and USA have published the annotated sequence of chromosome 1. 17/05/06
Image for Chromosome 17: an evolutionary black sheep
Though often mocked, the rare exceptions to the norm can sometimes be particularly instructive. And among human chromosomes, chromosome 17 is indeed an important exception. 27/04/06
Image for Chromosome 11 sequence complete
Of all the chromosomes that adorn the human genetic landscape, few have as full a past as chromosome 11. 23/03/06
Image for Chromosome 12 annotated sequence complete
Researchers from Baylor College of Medicine's Human Genome Sequencing Center have published the annotated sequence of chromosome 12. 16/03/06
Image for Marsupial genome sheds light on the evolution of immunity
The genetic code of the gray, short-tailed opossum reveals insights into the evolution of the major histocompatibility complex. 30/01/06
Image for Human chromosome 18 completed
Barren but not a wasteland. 22/09/05
Image for Human Y chromosome stays intact while chimp Y loses genes
The human and the chimpanzee Y chromosomes went their separate ways approximately 6 million years ago. But ever since this evolutionary parting, these two chromosomes have experienced different fates, new research indicates. 01/09/05
Image for Comparing the chimpanzee and human genomes
The first comprehensive comparison of the genetic blueprints of humans and chimpanzees shows that our closest living relatives share perfect identity with 96 per cent of our DNA sequence. 31/08/05
Image for Scientists analyse chromosomes 2 and 4
Detailed analysis of chromosomes 2 and 4 detects the largest 'gene deserts' known in the human genome and uncovers more evidence that human chromosome 2 arose from the fusion of two ancestral ape chromosomes. 06/04/05
Image for X chromosome unveiled
New insights into the role of sex chromosomes in health and disease. 17/03/05
Image for Chicken genome sequenced
Genome analysis of the red jungle fowl, a wild ancestor of the domestic chicken, is completed by an international consortium. 09/12/04
Image for Reconstructing the genome of a common mammalian ancestor
Researchers have re-created part of the genome of the common ancestor of all placental mammals that lived more than 80 million years ago. 30/11/04
Image for Finished human genome contains even fewer genes than expected
The International Human Genome Sequencing Consortium has published an analysis of the 'gold standard' version of the human genome sequence, and has reduced the human genome number to 20-25 000. 21/10/04
Image for Mice thrive without 'junk DNA'
Researchers have deleted 3 per cent of the mouse genome, but the mice show no apparent ill effects. 20/10/04
Image for Human chromosome 5 completed
Researchers reach the halfway point in dotting the i's and crossing the t's of the final human genome. 15/09/04
Image for Human chromosomes 9 and 10 completed
One-tenth of the human genome is unveiled. 27/05/04
Image for Gene-poor chromosome 13 sequence completed
Researchers from the Wellcome Trust Sanger Institute have completed the sequence of human chromsome 13. 01/04/04
Image for Gene-rich human chromosome 19 sequence completed
The sequencing of human chromosome 19 has been completed by the United States Department of Energy Joint Genome Institute (JGI) and Stanford University. 31/03/04
Image for Rat genome compared with human, mouse
The draft sequence of the genome of the Brown Norway strain of the laboratory rat (Rattus norvegicus) is completed. 31/03/04
Image for Celera to release genome data
Celera Genomics, the company that 'raced' the public Human Genome Project to finish sequencing the human genome, will be depositing its human genome sequence, once only available by subscription, into the online database GenBank. 19/02/04
Image for Chromosome 6 unravelled
The largest chromosome completed to date has many genes for the human immune system. 23/10/03
Image for Sequence of human chromosome 7 finalised
The final, high-accuracy sequence of human chromosome 7 has been completed - joining the sequences of chromosomes 14, 20, 21, 22 and Y. 10/07/03
Image for Y chromosome sequence unveiled
The DNA sequence of the human Y chromosome - the 'maleness' chromosome - has been published. 16/06/03
Image for Human genome sequencing completed
The International Human Genome Consortium has announced the successful completion of the Human Genome Project more than two years ahead of schedule. 14/04/03
Image for Mouse genome sequence draft published
An international consortium has published a draft sequence and analysis of the genome of the common mouse, Mus musculus. 05/12/02
"When results are shared freely amongst the biological community, as has been done for the worm and the Human Genome Projects, specialist scientists can move much more rapidly towards their goals." John Sulston
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